Explore Cartagena’s colonial architecture, picturesque squares and historic sites that offer a glimpse into the city’s dramatic past, including infamous pirates and the Spanish Inquisition. After you cruise through the Panama Canal – one of the Seven Wonders of the Modern World – dive into the region’s history with a visit to the 16th century ruins of Panamá Viejo and savor local cuisine in the vibrant metropolis of the capital city.